Endocrinology Research and Practice
Case Report

Postpartum Lactation Failure Secondary to Isolated Prolactin Deficiency: A Case Report and Literature Review


Department of Internal Medicine, Atatürk University Faculty of Medicine, Erzurum, Turkey


Division of Endocrinology and Metabolism, Department of Internal Medicine, Ataturk University Faculty of Medicine, Erzurum, Turkey

Endocrinol Res Pract 2022; 26: 97-99
DOI: 10.5152/tjem.2022.22048
Read: 3576 Downloads: 707 Published: 01 June 2022

Prolactin deficiency can occur alone, as can be seen by the deficiency of 1 or more of the other ante- rior pituitary hormones. Isolated prolactin deficiency is an extremely rare condition, and the only known symptom is the lack of lactation in postpartum women. A 29-year-old female presented in 2 weeks postpartum for evaluation of lactation failure. On the postpartum 16th day, the prolactin level was very low. Since there were no other pituitary abnormalities, we considered the diagnosis of isolated prolactin deficiency. In this case, we presented lactation failure due to isolated prolactin defi- ciency, which is extremely rare in the literature. In isolated prolactin deficiency, most of the patients are diagnosed with the absence of lactation and there are no other concurrent pituitary pathologies. In the treatment, recombinant human prolactin stands out as an option, but it is unavailable in many countries. In most cases, baby formula is used to feed babies.

Cite this article as: Bilen A, Bilen H, Güngör Albayrak E, Karadeniz Y, Gökkaya N. Postpartum lactation failure secondary to isolated prolactin deficiency: A case report and literature review. Turk J Endocrinol Metab. 2022;26(2):97-99.

EISSN 2822-6135