Paragangliomas are catecholamine-secreting neuroendocrine tumors originating from extra- adrenal neural crest cells. Urinary bladder paragangliomas are extremely rare and usually present with micturition-related hypertension, palpitations, headaches, dizziness, and sweating. We report a middle-aged female with a giant urinary bladder paraganglioma that was symptomatic for 6 years but unfortunately remained undiagnosed for more than half a decade. The patient exhibited the typi- cal noradrenergic biochemical phenotype that characterizes paragangliomas. The patient was suc- cessfully managed with subtotal cystectomy and augmentation cystoplasty. Ours is the patient with largest reported case of urinary bladder paraganglioma and the only one managed with augmenta- tion cystoplasty.
Cite this article as: Misgar RA, Baba MS, Bhat AH, et al. A giant urinary bladder paraganglioma. Turk J Endocrinol Metab. 2022;26(2):100-102.