Evaluation of Mild Hyperglycemia During Early Pregnancy

Hyperglycemia and its association with adverse pregnancy outcomes have been comprehensively described in the literature. Moreover, researchers have just about reached a consensus regarding the diagnostics and intervention algorithms for hyperglycemia after the 24th week of pregnancy. However, diagnostic thresholds and intervention algorithms remain controversial during the early pregnancy period. Hyperglycemia, especially during the organogenesis period, may promote serious adverse fetal outcomes like congenital malformations. In this regard, several guidelines have released varying recommendations. We aimed to summarize the current literature regarding the evaluation of mild hyperglycemia during the early pregnancy period. Patients diagnosed with diabetes mellitus in the first trimester based on internationally accepted diagnostic criteria for the general population are beyond the scope of the current article.

Cite this article as: Doğruel H, Aydemir M, Sarı R. Evaluation of mild hyperglycemia during early pregnancy. Endocrinol Res Pract. Published online May 27, 2024. doi: 10.5152/ erp.2024.23394