Endocrinology Research and Practice
Original Article

A Cross-Sectional Study of the Prevalence of Cardiovascular Disease in Adults with Type 2 Diabetes in Türkiye: The CAPTURE Study


Division of Endocrinology and Metabolism, Erciyes University Faculty of Medicine, Kayseri, TURKIYE


Division of Endocrinology and Metabolism, Zonguldak Bülent Ecevit University Obesity and Diabetes Application and Research Center, Zonguldak, TURKIYE


Department of Family Medicine, İstanbul Medeniyet University Faculty of Medicine, İstanbul, TURKIYE


Division of Endocrinology and Metabolism, İnönü University Faculty of Medicine, Malatya, TURKIYE


Division of Endocrinology and Metabolism, Trakya University Faculty of Medicine, Edirne, TURKIYE


Medical and Scientific Affairs Department/CMRQ, Novo Nordisk Health Products Tic. Ltd. Şti., İstanbul, TURKIYE


Division of Endocrinology and Metabolism, University of Health Sciences Gülhane Faculty of Medicine, Ankara, TURKIYE

Endocrinol Res Pract 2022; 26: 1-12
DOI: 10.25179/tjem.2021-86803
Read: 3029 Downloads: 720 Published: 01 March 2022


Objective: The primary objective of the CAPTURE study was to estimate the prevalence of cardiovascular disease (CVD) in adults with Type 2 diabetes mellitus (T2DM) across 13 countries from 5 continents. Here, we present the findings from Türkiye. Material and Methods: The non-interventional, cross-sectional CAPTURE study (NCT03811288; NCT03786406) was conducted across 15 centers in Türkiye. Standardized demographic and clinical data were collected from adults with T2DM who were treated by primary or specialist care physicians. The prevalences of CVD and its 7 subtypes were estimated. Descriptive statistics were used for data analysis. Results: Amongst the 801 participants (n=200 from primary care, n=601 from specialist care) with T2DM enrolled, 250 had established CVD, an estimated weighted prevalence of 31.2% (28.0-34.4) 95% confidence interval. Atherosclerotic CVD contributed to the majority (85.6%) of the CVD cases. An estimated 24.0% of the Türkiye sample had coronary heart disease (CHD). Heart failure was the second most predominant CVD subtype in Türkiye is correct sample (5.4%), followed by cardiac arrhythmia and conduction abnormalities (4.7%). Sodium-glucose co-transporter 2 inhibitors and glucagon-like peptide-1 receptor agonists with cardiovascular (CV) benefits were prescribed to 17.5% and 0.1% of the patients, respectively. Conclusion: Approximately 30% of participants with T2DM had established CVD in the CAPTURE Türkiye population, comparable to the global pooled prevalence. CHD was the major contributor and encompassed approximately 75% of the CVD cases. The use of glucose-lowering medication with CV benefits was low compared to the global pooled population, which may be due to the lack of reimbursement of these medications in Türkiye.



EISSN 2822-6135