ABSTRACT
Recent epidemiological data have established a link between vitamin D deficiency and type 1 and type 2 diabetes mellitus (DM). Experimental evidence also supported the idea that vitamin D may play a role in the pathogenesis of DM. Additionally, it has been reported that vitamin D supplementation may decrease the risk of developing DM in long term period. The protective effects of vitamin D are mediated through the immune system and calcium metabolism. Vitamin D may also have a direct effect on pancreatic beta cells.