Endocrinology Research and Practice
Poster Presentation

Visceral Adiposity Index Levels in Patients with Hypothyroidism


The Department of Family Medicine, Konya Health Application and Research Center, University of Health Sciences, Konya, Turkey


The Department of Internal Medicine, The Division of Endocrinology and Metabolism, The Medical School of Usak University, Uşak, Turkey


The Department of Family Medicine, Meram Medical School of Necmettin Erbakan University, Konya, Turkey


The Department of Statistics, Necmettin Erbakan University, Faculty of Science, Konya, Turkey


The Department of General Surgery, Konya Health Application and Research Center, University of Health Sciences, Konya, Turkey

Endocrinol Res Pract 2018; 22: Supplement S66-S67
DOI: 10.25179/tjem.20182202-P205
Read: 768 Downloads: 278 Published: 01 June 2018


Objective: To assess visceral adiposity index (VAI) as a sign of cardio-vascular diseases (CVD) in patients with overt or subclinical hypothyroidism.
Materials and Methods: Sixty-eight patients with hypothyroidism (29 with overt and 39 with subclinical hypothyroidism) and 33 age- and gender-matched control patients were included. VAI levels were calculated with the following formula: (waist circumference (WC)/[36.58+(1.89xbody mass index (BMI))])x[(triglyceride (TG) (mmol/L)/0.81)x (1.52xhigh-density lipoprotein cholesterol (HDL-cholesterol) (mmol/L))] and (WC/[39.68+(1.88xBMI)])x[(TG (mmol/L)/ 1.03)x(1.31xHDL-cholesterol (mmol/L))], respectively.
Results: While body weight (p<0.01), BMI (p<0.01), TG and VAI levels (p<0.01) were higher in patients with hypothyroidism than controls. HDL-cholesterol levels were lower (p=0.02) (Table 1). When patients were divided to groups as subclinical (n=39) and overt hypothyroidism (n=29) and compared with each other and controls (n=33) (Table 2), body weight (p=0.02 and p=0.02, respectively), BMI (p=0.01 and p<0.01, respectively) and TG (p<0.01 and p=0.03, respectively) were higher in overt and subclinical hypothyroidism groups than controls. HDL-cholesterol was lower only in the group with overt hypothyroidism than controls (p=0.01). Although found similar to each other in overt and subclinical hypothyroidism groups. VAI levels were observed to be higher in both groups than controls (p<0.01 and p=0.02, respectively). In correlation analysis, a positive correlation was determined between thyroid stimulating hormone (TSH), BMI and VAI levels (p=0.03 and p<0.01, respectively).
Conclusions: Due to the association between increased VAI levels and CVDs, we consider that several measures should be promptly taken to decrease these risk factors in patients with hypothyroidism.

EISSN 2822-6135