Thyrotoxic Hypokalaemic Periodic Paralysis (TPP) in Turkey: Report of a Case and Review of the Literature

Abstract

Thyrotoxic hypokalaemic periodic paralysis (TPP) is characterized by acute and reversible episodes of muscle weakness during thyrotoxicosis and associated with low potassium levels. Increased sodium-potassium ATPase activity in TPP leads to sudden influx of potassium into muscle cells and results in hypokalaemia. It is seen most commonly in Southeast Asian men. TPP is a rare condition in our country. Although only three patients were reported from Turkey in the English literature, there are Turkish cases reported in the national literature. Here we report a case of TPP due to toxic nodular goiter and review the literature.