Endocrinology Research and Practice
Original Article

The Role of Genetic Density in Development of Diabetic Retinopathy

1.

Istanbul University, Insitute for Experimental Medicine, Istanbul, Turkey

2.

Istanbul University, Istanbul Faculty, of Medical Department of Public Health, Division of Statistics and Demography, Istanbul, Turkey

3.

Istanbul University, Istanbul Medical Faculty Internal Medicine Department Diabetes Division, Istanbul, Turkey

Endocrinol Res Pract 1997; 1: -
Read: 1445 Published: 17 March 2022
ABSTRACT
The relation between the family history of diabetes mellitus (DM) and the prevalence of diabetic retinopathy (DR) and its severity is investigated in patients with Type U diabetes. This study comprises the family trees up to the third degree (including) of 364 patients. The diabetic persons in all these three - degree relatives were counted. The incidence of preproliferative + proliferative DR with 10 years or less of duration of DM was significantly higher in patients with number of diabetic relatives 3 and more (p < 0.01). But this difference was not significant in patients with a duration of diabetes more than 10 yrs (p > 0.5). As a result, our findings indicate a genetic component for developing severe DR.
 
EISSN 2822-6135