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ABSTRACT
Polycystic ovary syndrome (PCOS) which is commonly associated with insulin resistance is one of the most common endocrine disorders in women. In order to determine the prevalence of glucose intolerance in women with PCOS in our region, we have performed OGTT in 46 women who were diagnosed as PCOS. Fiftheen healthy women served as a control group. Glucose tolerance was abnormal in 10 (21.7%) women: 8 (17.4% ) had impaired glucose tolerance (IGT) and 2 (4.3%) had type diabetes mellitus. Women with PCOS had significantly higher basal and stimulated insulin levels. These results show that the prevalence of IGT and Type 2 diabetes mellitus was higher in women with PCOS than expected in general population. We think that women with PCOS should be evaluated not only with reference to the gynecological aspects but also the metabolic aspects of the disease.
Polycystic ovary syndrome (PCOS) which is commonly associated with insulin resistance is one of the most common endocrine disorders in women. In order to determine the prevalence of glucose intolerance in women with PCOS in our region, we have performed OGTT in 46 women who were diagnosed as PCOS. Fiftheen healthy women served as a control group. Glucose tolerance was abnormal in 10 (21.7%) women: 8 (17.4% ) had impaired glucose tolerance (IGT) and 2 (4.3%) had type diabetes mellitus. Women with PCOS had significantly higher basal and stimulated insulin levels. These results show that the prevalence of IGT and Type 2 diabetes mellitus was higher in women with PCOS than expected in general population. We think that women with PCOS should be evaluated not only with reference to the gynecological aspects but also the metabolic aspects of the disease.