Tamoxifen Treatment for Riedel’s Thyroiditis: A Case Report

Riedel’s thyroiditis is a rare variant of thyroiditis, and treatment recommendations are based on case reports. This thyroiditis form is considered among immunoglobulin G4-related diseases. Intense fibrosis of the thyroid gland can cause compression of the surrounding tissues and hypothyroidism. Glucocorticoids are recommended as first-line therapy, and tamoxifen is second-line therapy. Other immunosuppressive agents have also been used in some resistant cases. Our case was presented with a palpable firm mass in the neck, shortness of breath, and hypothyroidism. The exact diagnosis of Riedel’s thyroiditis was made after a pathological examination of a true-cut biopsy. We present the successful management of this case with glucocorticoid and tamoxifen combination treatment.

Cite this article as: Karakılıç E, Saygılı ES, Yildiz O, Kuyucu A. Tamoxifen treatment for Riedel’s thyroiditis: A case report. Endocrinol Res Pract. 2023;27(4):245-247.