Spontaneous Successful Pregnancy in Post-Surgical Hypopituitarism: A Case Report

Abstract
Pregnancy in patients with panhypopituitarism is rare and considered high risk. Since the availability of ovulation induction with gonadotrophins, women with established hypopituitarism can expect near normal fecundity and the pregnancy outcome is better with support of the replacement of deficient hormones. We present a case of non-functioning pituitary macroadenoma, who after pituitary surgery developed hypopituitarism. The patient had secondary amenorrhea as part of hypopituitarism and was on thyroxine, prednisolone and a combination of estrogen and progesterone. She conceived and carried her pregnancy to the term. Elective caesarean section was done at 37 weeks and both infant and mother are well. The case highlights the rarity of the phenomenon and the safe outcome of the pregnancy with proper replacement.