Endocrinology Research and Practice
Original Article

Serum 25(OH) Vitamin D Levels in Severely Obese Patients Evaluated Before Bariatric Surgery


Marmara University Pendik Training and Research Hospital, Clinic of Internal Medicine, İstanbul, TURKEY


Marmara University Faculty of Medicine, Department of Endocrinology and Metabolism İstanbul, TURKEY

Endocrinol Res Pract 2020; 24: 115-121
DOI: 10.25179/tjem.2019-71778 -
Read: 2097 Downloads: 667 Published: 01 June 2020


Objective: Obesity is a risk factor for vitamin D deficiency, which is reported to be detected differently in each population. This study aimed to evaluate the 25(OH) vitamin D (25(OH)D) levels, intact parathormone (iPTH) levels, and their relationship with body mass index (BMI) in obese patients, screened prior to bariatric surgery. Material and Methods: This retrospective study comprised of 1.082 obese patients (41±10 years, female/male: 823/259) who were candidates for bariatric surgery. BMI, waist circumference (WC), serum 25(OH)D, iPTH, calcium, phosphorus values of these patients were recorded from patient files. Results: BMI, WC, iPTH, and 25(OH)D levels were 48±8.9 kg/m², 128±11.9 cm, 64±36 pg/mL, and 15±18 ng/mL, respectively. Mean 25(OH)D level of 79.1% of the patients belonged to the deficiency range. Very low 25(OH) vitamin D levels (<10 ng/mL) were witnessed among 40.9% (443/1.082) of the study group. Female obese subjects possessed significantly lower serum 25(OH)D levels as compared to male obese patients. Significant negative correlations were perceived between 25(OH)D levels and iPTH (r=-0.34, p<0.0001), BMI (r=-0.20, p<0.0001), and waist circumferences (r=-0.14, p=0.002) in the whole group. Multivariate analysis indicated that BMI to be an independent risk factor for vitamin D deficiency. Conclusion: A high rate of vitamin D deficiency was documented in our morbidly obese patients who were candidates for bariatric surgery. BMI is a determinant of 25(OH)D levels. It is essential to screen for vitamin D deficiency and possible osteomalacia among the candidates for bariatric surgery of obese patients and should be treated appropriately before bariatric surgery.



EISSN 2822-6135