Endocrinology Research and Practice
Case Report

Propylthiouracil-Induced Thrombotic Leukocytoclastic Vasculitis

1.

Medical Faculty of Istanbul University, Endocrinology and Metabolism, Istanbul

Endocrinol Res Pract 2006; 10: 45-47
Read: 1432 Downloads: 496 Published: 01 June 2006

Abstract

Antithyroid drug therapy with Propylthiouracil (PTU) is commonly used in Graves’ disease. One of the most serious complications of this drug is PTU-induced leukocytoclastic vasculitis. We report a 23 year-old woman who developed leukocytoclastic vasculitis which is a rare and serious side effect during PTU therapy for Graves’ disease. The observation of cutaneous vasculitis in this patient during administration of PTU indicates that reguler follow-up of patients on antithyroid drug regimen is mandatory.


 

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