Medical Therapy of Acromegaly

Abstract

Acromegaly is a chronic disorder associated with increased mortality and morbidity. There are several studies have shown that mortality rate of acromegalic patients become similar to normal population when normal GH values are achieved. Surgery is the first line treatment of acromegaly. But the remission rates with surgery alone are low. Therefore, it is necessary to add other treatment modalities. Such as somatostatin anlogs, dopamin agonists, GH receptor antagonists and radiotherapy.