Markedly Elevated Troponin in Diabetic Ketoacidosis without Acute Coronary Syndrome

ABSTRACT

Troponin gives excellent accuracy in the identification of myocardial necrosis, however, it may elevate also in a series of non-atherosclerotic heart diseases. We report the case of a 58-year-old woman with diabetic ketoacidosis (DKA). She had markedly increased levels (90 fold) of cardiac biomarkers (troponin I and CK-MB) and initial electrocardiography changes compatible with myocardial infarction. She had normal a coronary angiogram. This case shows that nonspecific myocardial injury may occur in DKA with the findings mimicking myocardial infarction including increased level of cardiac biomarkers and electrocardiography changes.