Lupus Anticoagulant Positivity in Autoimmune Thyroid Diseases

Abstract
Objective: Autoimmune thyroid diseases are often concomitant with the other autoimmune diseases. In this study, our aim was to assess the presence of lupus anticoagulant, which is an antibody involved in the etiology of thrombosis, in patients with autoimmune thyroid diseases.
Materials and Methods: A total of 118 thyroid patients and 54 healthy controls were involved in the study. The coagulation system parameters, thyroid function tests, ANA, anti-dsDNA, anti-TG, anti-TPO, and LA were analyzed.
Results: Lupus anticoagulant was found in 41.5% of the patients, in 5.63% of the control group, 45.9% of the patients with positive anti-thyroid autoantibody, 36.8% of the patients with negative anti-thyroid autoantibody. No statistically significant correlation was found between presence of LA and thyroid disease type or presence of autoantibodies.
Conclusions: The presence of LA was higher in patients than controls (P=0.001).