Late Diagnosed Type II Autoimmune Polyglandular Failure Syndrome: A Case Report

ABSTRACT

Autoimmune polyglandular syndrome (APS) type II is the term descibing a group of diseases with two or more concurrent endocrine disorders. It is more prevalent in female gender. The most common pathologies include primary adrenal insufficiency (Addison’s disease), autoimmune thyroid diseases (Graves’ disease, Hashimoto’s thyroiditis), type 1 diabetes mellitus (DM) and primary hypogonadism. Replacement of deficient hormone is the basis of treatment. The present paper discussed autoimmune polyglandular syndrome based on the symptoms in a 25-year-old female patient who was followed in the intensive care unit because of impaired consciousness considered to have resulted from potential drug/substance addiction. Antidepressant therapy was recommended for the patient and she was diagnosed with APS on further evaluation.