Isolated Adrenocorticotropic Hormone Deficiency (ACTH) Associated with Hashimoto's Disease

ABSTRACT

Isolated adrenocorticotropic hormone (ACTH) deficiency (IAD) is a rare disease characterized by secondary adrenal insufficiency with low cortisol production and normal secretion of pituitary hormones other than ACTH. Association of IAD with Hashimoto’s disease (HD) is rare. This suggests the possibility of common autoimmune process affecting both the pituitary and the thyroid glands. Here, we report two cases of IAD with HD.