Graves' Disease With Unilateral Involvement: A Rare Entity

ABSTRACT

Graves’ disease usually affects both lobes of the gland, thus, unilateral Graves’ hyperthyroidism has been reported very rarely. Here, we report a case of Graves’ disease presenting with unilateral involvement of the thyroid gland. Thyroid function tests revealed thyrotoxicosis and scintigraphy with technetium-99m  showed increased diffuse unilateral radioisotope uptake in the right lobe with suppressed activity in the left lobe. The patient underwent oral antithyroid drug treatment. Graves’ disease may present with asymmetrical uptake on thyroid scan similar to asymmetrical Graves’ ophthalmopathy.