Endocrinology Research and Practice
Review Article

Ghrelin

1.

Ankara Numune Education and Research Hospital, Department of Endocrinology and Metabolism Diseases, Ankara

2.

Ankara Education and Research Hospital, Department of Internal Medicine

3.

Ankara Atatürk Education and Research Hospital, Department of Endocrinology and Metabolism, Ankara, Turkey

Endocrinol Res Pract 2002; 6: 59-68
Read: 1444 Downloads: 499 Published: 25 March 2022
ABSTRACT
Growth hormone secretagogues are synthetic peptidyl and non- peptidyl molecules that possess growth hormone releasing activity. Ghrelin is an endogenous natural ligand for the growth hormone secretagogue receptor that has recently been isolated from the rat stomach. Ghrelin administration stimulates growth hormone secretion but also causes weight gain by increasing food intake. Ghrelin’s structural features, secretion patterns, secretion sites, mechanisms of action and interactions and its possible involvement in obesity are still investigated.
 
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EISSN 2822-6135