Comparison of Electrochemiluminescence and Enzyme Immunoassay Methods for the Measurement of Salivary Cortisol

ABSTRACT

Purpose: The aim of the study was to compare electrochemiluminescence (ECL) and enzyme immunoassay (EI) methods for the measurement of salivary cortisol (SC).
Material and Method: SC levels in 20 healthy subjects were measured by two different methods (EI and ECL).
Results: The results obtained from EI and ECL methods were found to be significantly correlated.
Discussion: Measuring SC by ECL method is faster and easier than EI in routine practice. Therefore, SC measured by ECL rather than EI may be used as a marker of hypothalamic-pituitary-adrenal (HPA) axis function.