A case of Anterior Pituitary Failure Associated with Ectopic Neurohypophysis

ABSTRACT

Ectopic neurohypophysis is an anomaly of the pituitary gland. This syndrome is characterized by ectopic neurohypophysis hyperintense signal on magnetic resonance imaging (MRI). Absence of pituitary stalk visibility and anterior hypophysis hypoplasia may also present. Sensitivity of MRI for pituitary stalk is increased by gadolinium injection. Visibility of the pituitary stalk is related to isolated growth hormone (GH) deficiency. In patients with no visible pituitary stalk on MRI after gadolinium injection, GH deficiency is expected during first years of life. Then anterior pituitary failure usually occurs on second and third decade of life. In this repor, we present a case of ectopic neurohypophysis in which the diagnosis of late-diagnosed anterior pituitary function failure was established at advanced age.