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Abstract
Objective: It was found that vitamin D has effect on insulin secretion and insulin sensitivity as well as bone health. The aim of the study; 1. to determine the 25-hydroxy vitamin D (25-OH D) levels in elderly with type 2 diabetes. 2. to assess the relationships between 25-OH D levels and fasting blood glucose (FBG) and postprandial blood glucose (PBG) and HbA1c levels.
Material and Methods: One houndred fifty five diabetic patients ≥65 years of age (mean age= 72.4±6.2 years (127 female, 28 male), were enrolled in the study. Demographic caracteristics, 25-OH D, biochemical tests were evaluated retrospectively.
Results: Mean level of 25-OH D was found to be 37.9±5.1 ng/mL. 25-OH D levels were <30 ng/mL in twenty seven percent of these patients. Mean levels of FBG and PBG and HbA1c were 149.5±14.5 mg/dL, 227.0±23.9 mg/dL and 8.2±1.8%, respectively. There was a negative correlation between 25-OH D levels and PBG (r=-0.200, p=0.02) in patients. In patients who had 25-OH D levels below 30 ng/mL, mean levels of 25-OH D correlated negativelly with FBG (r= -0.700, p=0.0001) and with PBG (r=-0.200, p=0.02) and with HbA1c (r=-0.450,p=0.001). In diabetic elderly who had 25-OH D levels ≥30 ng/mL; there were no correlations between 25-OH D levels with FBG and PBG and- HbA1c.
Conclusion: Mean levels of 25-OH D were 37.9±5.1 ng/mL in the elderly with type 2 diabetes. There were negative correlations between mean levels of 25-OH D and fasting blood glucose and postprandial glucose and HbA1c in diabetic elderly who had 25-OH D levels below 30 ng/mL.